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The sitcom wins for a fifth year, while Ant and Dec, Jesy Nelson and Michael Palin are also honoured.
"Nobody wins a game on their first move," says the star, as she launches a new phase of her career.
The award-winning Channel 4 show will come from a new restaurant after seven years based in London.
The Volunteer, by ex-war reporter Jack Fairweather, beats four other books to the £30,000 award.
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